Skin Boostersin Seoul by Ingredient: PN, HA, PDLLA

Rejuran products contain polynucleotides, chains of DNA fragments that act as a scaffold in the skin. A pharmacology review traces the related compound PDRN to an effect on the adenosine A2A receptor, a pathway linked to wound healing in laboratory and clinical work (Squadrito, 2017). In cosmetic use, Rejuran Healer is spread over the whole face for texture and dull, thin skin, Rejuran HB comes as a 1 cc syringe, and Rejuran Eye is a 1 cc dose kept to the thin skin under and around the eyes.

A systematic review of nine polynucleotide studies with 219 participants reported improvement in wrinkles, texture and elasticity with mild, short-lived side effects, while judging the studies low to moderate in quality and calling for stronger trials (Lampridou, 2024). At ENTER Plastic Surgery, numbing cream goes on for 30 minutes before Rejuran, and the plan is three sessions four weeks apart, then a top-up every three to six months. The clinic holds a REJURAN Official Certified Clinic plaque from PharmaResearch, the product maker.

Hyaluronic acid binds water, and these boosters place it as very fine droplets in the upper skin layers for a hydrated, smoother surface. Skinvive comes as a 2 cc treatment. Here it is planned as one session, with a second one month later if your skin needs it, and repeat treatments come at six-month intervals; the clinic's guidance gives six to nine months for the result.

The water glow injection is a lighter hydrating treatment given with the Derma Shine injector. It is planned as three sessions four weeks apart, with three to six months as the clinic's figure for how long the effect lasts. Belotero Revive is a further hyaluronic acid booster on the menu, sold per 1 cc.

Juvelook Skin uses poly-D,L-lactic acid, a material the body breaks down slowly while collagen forms around it, so changes appear gradually and not on the day. The 4 cc dose is delivered with Cure Jet, a needle-free injector. The course is three sessions four weeks apart, and the clinic's guidance puts the result at six to twelve months. Deeper volume products such as Sculptra, Radiesse and Juvelook Volume belong with the collagen stimulators, which have their own page.

These four are branded skin boosters listed by name on the clinic menu. Their ingredients are described in each maker's own product literature, which this page does not restate. Re2O is planned as three sessions four weeks apart, it can be given by needle or by cannula depending on skin type, and the clinic's figure for the result is six to twelve months. Re2O Fine appears on the price list as a separate item. For CellREDM, GOURI and Tissivo, the treatment plan is set when your skin is examined.

Small raised bumps at the injection points flatten as the product absorbs over one to three days. Needle marks or bruises can stay for three to seven days, depending on the person. Keep water and makeup off the skin for three to four hours so the tiny punctures can close; makeup or concealer is fine from the next day. If anything unusual appears, such as spreading redness, heat or worsening pain, contact the clinic instead of treating it yourself.

Because the clinic's guidance allows a flight home on the same day or the next day, a single booster session fits a short stay. A course of three sessions four weeks apart is a different plan: it either means returning to Seoul, or starting the course here and talking through the remaining sessions. ENTER Plastic Surgery is registered with Korea's Ministry of Health and Welfare as a medical institution for international patients (registration M-2023-01-08-7461).